Biomimetic Mineralization of Calcium Phosphate Regulated by Different Bioorganic Molecules-OAJRC Cellular and Molecular Biology-Pubscie

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Biomimetic Mineralization of Calcium Phosphate Regulated by Different Bioorganic Molecules

DOI: 10.26855/oajrccmb.2022.12.002
Year, volume (issue): 2022, 4(1)
pp. 5-8
Published in: OAJRC Cellular and Molecular Biology
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BM Joshi

Different organisms, organic molecules, regulation, calcium phosphate, biomi-metic mineralization

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Abstract

Biomineralization is an important link in the formation of biological tissues. Cell self-assembly can be realized to a certain extent through the regulation of organic matrix. Therefore, it is very necessary to understand the mechanism of action of organic matrix in inorganic minerals. In this paper, experiments were performed on five organic biomolecules. The biomimetic mineralization of calcium phosphate by citric acid, aspartic acid, glutaric acid, lysine, bovine serum albumin , etc. was studied, and by changing its content and the concentration of calcium and phosphorus solutions, the calcium phosphate Type, shape and size. Using XRD, FTIR, SEM, DSC, TG and other methods, the influence of different bioorganic molecules on calcium phosphate was studied , and its regulation mechanism was studied.

Keywords: Different organisms, organic molecules, regulation, calcium phosphate, biomi-metic mineralization

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[1] Salama A. Recent progress in preparation and applications of chitosan/calcium phosphate composite materials[J]. International Journal of Biological Macromolecules, 2021, 178: 240-252.

[2] Shin K, Acri T, Geary S, et al. Biomimetic mineralization of biomaterials using simulated body fluids for bone tissue engineering and regenerative medicine[J]. Tissue Engineering Part A, 2017, 23(19-20): 1169-1180.

[3] Salama A, Shukry N, El-Gendy A, et al. Bioactive cellulose grafted soy protein isolate towards biomimetic calcium phosphate mineralization[J]. Industrial crops and products, 2017, 95: 170-174.

[4] Gleeson S E, Kim S, Qian Q, et al. Biomimetic Mineralization of Hierarchical Nanofiber Shish-Kebabs in a Concentrated Apa-tite-Forming Solution[J]. ACS Applied Bio Materials, 2020, 4(1): 571-580.

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[6] Guentsch A, Fahmy M D, Wehrle C, et al. Effect of biomimetic mineralization on enamel and dentin: A Raman and EDX analysis[J]. Dental Materials, 2019, 35(9): 1300-1307.

[7] Dash M, Samal S K, Morelli A, et al. Ulvan-chitosan polyelectrolyte complexes as matrices for enzyme induced biomimetic mineralization[J]. Carbohydrate polymers, 2018, 182: 254-264.

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[9] Abuna G, Feitosa V P, Correr A B, et al. Bonding performance of experimental bioactive/biomimetic self-etch adhesives doped with calcium-phosphate fillers and biomimetic analogs of phosphoproteins[J]. Journal of dentistry, 2016, 52: 79-86.

[10] Gil J, Manero J M, Ruperez E, et al. Mineralization of titanium surfaces: Biomimetic implants[J]. Materials, 2021, 14(11): 2879.

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